Zoster-Associated Complications

Postherpetic neuralgia—the most common zoster complication—can result in severe, chronic pain.7,12

Allodynia—90% of patients with postherpetic neuralgia develop allodynia—distressing and debilitating pain caused by even the slightest touch.7,11

Patients have described postherpetic neuralgia as burning, throbbing, stabbing, shooting, and/or sharp pain.7

  • Postherpetic neuralgia can persist for months or even years.9
  • Chronic neuropathic pain will develop in a subgroup of zoster patients despite appropriate antiviral treatment.2

Ophthalmic zoster—Zoster ophthalmicus occurs in >10% of all zoster cases and can lead to visual morbidity.

Severe zoster ophthalmicus—Photograph reprinted with permission from Pavan-Langston D. Ophthalmic zoster. In: Arvin AM, Gershon AA, eds. Varicella-Zoster Virus: Virology and Clinical Management. Cambridge, UK: Cambridge University Press; 2000:276—298.13

Zoster complications may include bacterial superinfection and scarring.7

Increasing age, increasing risk–Learn more about zoster incidence